What kind of substance is olestra




















A lot of evidence suggests that these nutrients may protect you against heart disease, prostate cancer and degeneration of the macula, the part of your eye that lets you see fine details like newsprint. In clinical studies, people who ate olestra had reduced carotenoid levels in their blood. However, since researchers still aren't quite sure how or even if carotenoids might prevent these diseases, it's hard to say whether olestra's effect on carotenoid levels is harmful to health.

Olestra also has one drawback common to many indigestible substances like dietary fiber or cellulose.

These substances simply pass straight through your system, so eating too much at once can cause you some problems. Sign up for our Newsletter! Mobile Newsletter banner close. Mobile Newsletter chat close. Mobile Newsletter chat dots.

Mobile Newsletter chat avatar. Mobile Newsletter chat subscribe. Food Processing. How does olestra work? The full fat chips have calories and 10 grams of fat per serving. The vast majority of people can thoroughly enjoy snacks made with Olean cooking oil, and will not notice any effects. In fact, a recent study published in the Journal of the American Medical Association January 14, found that people eating Olean chips report no more digestive symptoms than those eating full-fat chips in a single sitting.

A nationwide survey conducted before Olean snacks were ever sold found that 41 percent of people reported one or more digestive symptoms within the month prior to the survey. This shows that digestive effects are very common, and can have many causes.

Woodworth M. Feisullin S. Beall P. Characterization of the Yucatan miniature pigs skin and small intestine for pharmaceutical applications. Lafranconi W. Long P. Atkinson J. Knezevich A. Wooding W. Lack of chronic toxicity and carcinogenicity of olestra in Swiss CD-1 mice. Leary H. Lecce J. Uptake of macromolecules by enterocytes on transposed and isolated small intestine. Leigh-Browne G. Harpur R. Intestinal intubation in the unanesthetised miniature pig: technique for sampling and measurement of gut length per fistulam.

Maas M. Hopman W. Katan M. Jansen J. Sucrose polyester does not inhibit gastric acid secretion or stimulate cholecystokinin in men. Kuehlthau C. The effect of a non-absorbable fat, sucrose polyester, on the metabolism of vitamin A by the rat.

The effect of a nonabsorbable lipid, sucrose polyester, on the absorption of dietary cholesterol by the rat. Volpenhein R. Hydrolysis of fully esterified alcohols containing from one to eight hydroxyl groups by the lipolytic enzymes of rat pancreatic juice. Lipid Res. Mellies M.

Taube J. Tewksbury M. Lamkin G. Baehler L. King P. Boggs D. Goldman S. Gouge A. Tsang R. A double-blind placebo-controlled study of sucrose polyester in hypercholesterolemic outpatients. Vitale C. The substitution of sucrose polyester for dietary fat in obese, hypercholesterolemic outpatients. Middleton S. Dwyer J. An indirect assessment of olestra's nutritional effects in healthy subgroups of the population. Miller E. Ullrey D. The pig as a model for human nutrition.

Madison B. Okenfuss J. Hudson P. Wilson S. Thorstenson J. Disposition of ingested olestra in the Fischer rat. Williams D. Carter S. Mishell D. The effect of olestra on systemic levels of oral contraceptives.

Wood F. Staurd S. Alden C. A month olestra feeding study in dogs. Nolen G. Dierckman T. A two-generation reproductive and developmental toxicity study of sucrose polyester. Nuck B. Federle T. Inability of the human colonic microflora to metabolize the nonabsorbable fat substitute, olestra.

Olson J. Serum levels of vitamin A and carotenoids as reflectors of nutritional status. Cancer Inst. Triebwasser K. Assessment of the nutritional effects of olestra, a nonabsorbed fat replacement: summary. Reinhold J. Faradji B. Abadi P. Ismail-Beigi F. Decreased absorption of calcium, magnesium, zinc, and phosphorus by humans due to increased fiber and phosphorus consumption as wheat bread. Rizzi G. Taylor H.

A solvent-free synthesis of sucrose polyester. Roberts R. Leff R. Influence of absorbable and nonabsorbable lipids and lipidlike substances on drug bioavailability.

Rossander L. Effect of dietary fiber on iron absorption in man. Sauberlich H. Hodges R. Wallace D. Kolder H. Canham J. Hood J. Raica N. Lowry L. Vitamin A metabolism and requirements in the human studied with the use of labeled retinol. McEdwards J. Dugan L. Davidson M. Olestra's effect on vitamins D and E in humans can be offset by increasing the dietary levels of these vitamins. Torri S. Olestra dose response on fat-soluble and water-soluble nutrients in humans.

Siigur U. Norin K. Midvedt T. Effect of olestra on faecal water and short-chain fatty acids. Health Dis. Mummah-Schendel L. Shah D. Lyle B. Greger J. Vitamin K deficiency from dietary vitamin K restriction in humans. Thompson J. Erdody P. Brien R. Murry T. Fluorometric determination of vitamin A in human blood and liver.

Tumbleson , M. National Information , Springfield, VA. Vanderveen J. Glinsmann W. Fat substitutes: a regulatory perspective. Harrison G. Lee M. Huang M. Estimated consumption and eating frequency of olestra from savory snacks using menu census data. Tierney W.

Bolte H. Maurer J. Bruce R. Chronic toxicity and carcinogenicity studies of olestra in Fischer rats. Published as a supplement to The Journal of Nutrition. Guest editors for this supplement were John W. Ross, Pennsylvania State University, S. Henderson Bldg. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.

Sign In or Create an Account. Sign In. Advanced Search. Search Menu. Article Navigation. Close mobile search navigation Article Navigation. Volume Article Contents Abstract. Peters , John C.

Oxford Academic. Kenneth D. Suzette J. Middleton, Ph. Keith C. Cite Cite John C. Select Format Select format. Permissions Icon Permissions. Abstract Olestra is a mixture of polyesters formed from sucrose and fatty acids derived from edible fats and oils. Open in new tab Download slide.

Table 1 Information on the effects of olestra on the status of fat-soluble and water-soluble nutrients from pig and human studies From pig studies. From human studies. Determination of the amount of extra vitamin A required to offset the effect of olestra. Effect of olestra on the absorption of vitamin A and serum concentrations of carotenoids. Assessment of the effect of olestra on carotenoid absorption in real life.

Vitamin D The response of serum 25 OH D 2 concentration to olestra, in the absence and presence of a vitamin D-3 component. The response of serum concentrations of 1,25 OH 2 D and bone concentrations of ash, calcium, and phosphorus to olestra. Determination of the amount of extra vitamin D required to offset the effect of olestra. Vitamin E The response of liver, adipose and serum vitamin E concentrations to olestra. Determination of the amount of extra vitamin E required to offset the olestra effect.

The response of serum vitamin E concentration to olestra doses representing olestra intake from savory snacks. Determination of the amounts of extra vitamin K required to offset the effect of olestra on serum phylloquinone.

Vitamin B The response of vitamin B liver concentration and related hematological parameters to olestra. Response of vitamin B serum concentration and related hematological parameters to olestra.

Effect of olestra on the absorption of vitamin B Folate The response of serum folate concentration and related hematological parameters to olestra. The response of plasma and RBC folate concentrations and related hematological parameters to olestra. Zinc The response of liver, bone and serum zinc concentrations to olestra. The response of urinary zinc concentration to olestra. Calcium The response of bone dry weight, bone ash, calcium and phosphorus concentrations, and of serum parathyroid hormone concentration, to olestra.

The response of serum calcium concentration to olestra. Iron The response of liver and serum concentrations of total iron, serum total iron binding capacity and related hematological parameters to olestra. The response of serum concentrations of total iron and ferritin, serum total iron binding capacity and related hematological parameters to olestra. Macronutrients Effect of olestra on growth and feed efficiency data at exaggerated olestra intakes as pigs aged from weaning through sexual maturity.

Effect of olestra on the absorption of triglyceride. Open in new tab. Using the menu census survey to estimate dietary intake. FDA concluded that the label statement was no longer warranted. Normal fats consist of a glycerol molecule with three fatty acid tails attached.

However, Olestra is synthesized using a sucrose molecule, which can support from six to eight fatty acid chains [3] arranged radially like an octopus, and is too large to move through the intestinal wall. Olestra has the same taste and mouthfeel as fat, but since it does not contain glycerol and the fatty acid tails can not be removed from the sucrose molecule for digestion, it passes through the digestive system without being absorbed and adds no calories or nutritive value to the diet.

From a mechanical point of view, scientists were able to manipulate the compound in such a way that it could be used in place of cooking oils in the preparation of many types of food Nestle, , Since it contains fatty acid functional groups , Olestra is able to dissolve lipid-soluble vitamins such as vitamin D , vitamin E, vitamin K , and vitamin A , along with carotenoids.

Fat soluble nutrients consumed along with Olestra products are excreted along with the undigested Olestra molecules. To counteract this loss of nutrient, products made with Olestra are fortified with oil soluble vitamins to compensate for this loss to fecal matter. But, outside of the popular culture disapproval of the product, many consumers simply did not see the speedy results for which they had hoped from a product they saw as being a cure all. This was due to the fact that Olestra only dealt with the fat component of the overall dietary pattern of Americans.

Foods containing olestra do contain calories and many Americans believed that they could just eat more of them to compensate for the less "saved" Nestle Eating olestra chips was not a particularly efficient way to improve one's diet overall.

In , researchers discovered that Olestra helps facilitate the removal of dioxins from the body, as it apparently binds to dioxins in a manner similar to that of normal fats. This unexpected side effect may make the substance useful in treating victims of dioxin poisoning. Read what you need to know about our industry portal chemeurope. My watch list my.



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